Student: Benjamin DELBOS
Keywords:: Haptics, Simulation, Hands-on Training
Supervised with Richard MOREAU and Rémi CHALARD
Period: started in September 2021, to be defended in 2024
Financed by INSA Lyon
Scientific field and context:
This subject is in the field of medical robotics, more precisely haptic simulation for learning medical gestures, and responds directly to the expectation of the High Authority of Health: "Never the first time on a patient".
Ventricular drainage is commonly performed in neurosurgery departments or in the emergency
room. It consists of inserting a catheter into the brain, using a needle, until it reaches the frontal horn to drain cerebrospinal fluid for therapeutic or diagnostic purposes [1]. The clinical routine is to insert this needle blindly. The only indication of success is the sudden loss of resistance when the ventricle is reached [2].Currently, it is fundamental that a neurosurgeon be able to perform this gesture "by hand".Indeed, the assistance systems (e.g. ROSA robot [7]) are unusual and expensive. However, the learning of
this gesture is only performed by companionship: there is no effective simulator for training in this type of surgery (neither anatomical mannequins [3] nor current Virtual Reality simulators [4-6]). However, the risks of causing serious after-effects for the patient are high.
Objectives of the thesis:
The main objective consists in designing and prototyping a haptic simulator [8] for the training of the ventricular drainage gesture in neurosurgical operations. The haptic interface manipulated by the learner will be specific to this gesture in order to reproduce conditions close to reality. The gestures performed during real operations will be analyzed and processed in order to propose a tool for a fast and objective evaluation of gestures during simulations.
The simulator will have to be able to customize the training sessions based on data specific to each patient (preoperative MRI images) to reduce the risk of errors during the surgical procedure.
Scientific problems:
Expected contributions:
Research program and proposed scientific approach:
During the drainage, the surgeon will use the shape of the skull and in particular the position of the patient's nose and ears as anatomical landmarks. The first part of the project will focus on thedesign of a realistic skull/ear/nose combination. Indeed, during each ventricular puncture, the position of the hole through which the surgeon will insert the needle plays a major role in the
success of the procedure. In practice, the surgeon relies on the positioning of the ears and nose to choose the location of the cranial drilling. These organs also serve as a reference point when the needle is inserted. Finally, he uses the patient's skull as a support point during the procedure. For all these reasons, it seems necessary to design physical cranial reproductions allowing the
simulator to gain in realism. Different sizes of skulls can be developed for pediatric surgery. It will also be necessary to use tools similar to those used in the operating room in order to accentuate the immersion of the simulator. A needle substitute will have to be mounted on the robot and allow the same movements as the real needle.
It will be necessary to develop control laws on a Haption robot in order to realistically reproduce the sensation of needle penetration [12] through the brain and the ventricle. One can refer to the work of Ma. de los Angeles ALAMILLA-DANIEL on joint puncture [13] and to the various tests already carried out on the laboratory's test platform. This stage will require, among other things, a bibliographical study of the mechanical properties of the brain in order to be able to reproduce them with adapted and innovative control laws, always with the aim of pushing the realism of the haptic simulator to its paroxysm.
The third theme will deal with training and feedback. It will be necessary to work on the creation of an augmented universe allowing to navigate in the brain and to see the ventricle from the MRI images of the patients in which it will be necessary to be able to locate the trajectory of the needle [14]. This step is crucial in addressing the challenges of training new surgeons in this surgical
procedure. Indeed, the creation of an augmented environment allowing the observation of the brain following different MRI slices and showing the needle trajectory during ventricular puncture training will facilitate the feedback of the expert surgeon accompanying the novice. It will also allow the learner to contextualize and visualize his mistakes or success in a learning process.
Finally, it will be necessary to work on the feedback given to the learner following his training. To do this, it will be necessary to classify the operations of novices and experts in order to better identify the difficulties of the gesture and personalize the training of each novice. This theme could be based on some of the laboratory work that has already addressed this subject. Indeed, in the
context of the PhD work of M. SENAC [15], different machine learning methods have been implemented to analyze the gestures of novices and experts. The objective was to determine the characteristics of the gestures performed in order to highlight the differences between experts and novices and thus offer novices personalized training with dedicated exercises. Thus supervised and unsupervised methods were implemented and compared in order to find the most appropriate
methods in our case. This work already followed on from the work carried out in the laboratory as
part of Mrs CIFUENTES' doctoral thesis [16], which focused on the determination of objective
criteria for the analysis of medical procedures. Based on previous work, this approach will allow us
to optimize the learning curves of learners with personalized and targeted feedback.
References:
[1] Toma AK, Camp S, Watkins LD, Grieve J, Kitchen ND. External ventricular drain insertion
accuracy: is there a need for change in practice? Neurosurgery 2009;65(6):1197–200.
10.1227/01.NEU.0000356973.39913.0B
[2] Banerjee, P. Pat, et al. "Accuracy of ventriculostomy catheter placement using a head-and hand-
tracked high-resolution virtual reality simulator with haptic feedback." Journal of neurosurgery
107.3 (2007) : 515- 521
[3] Zhuang Jianghui, He Bingwei, et al. "Development and Application of a Simulated Puncture
Model for Lateral Ventricle". China Medical Equipment (2018), 33 (5), 32-35
[4] Manchester, Nigel John, and Nigel W. John. "A vrml simulator for ventricular catheterization.",
Eurographics UK, 1999.
[5] Luciano, Cristian, et al. "Second generation haptic ventriculostomy simulator using the
ImmersiveTouchTM system." Studies in health technology and informatics 119 (2005): 343.
[6] Zhongyi Chen, Yuqing Liu, et al. "Application of mixed reality-based lateral ventricle puncture
training system in medical education training" Electronic Journal of Trauma and Emergency (2019).
[7] Lefranc M, Capel C, Pruvot-Occean AS, Fichten A, Desenclos C, Toussaint P, Le Gars D, Peltier J.
Frameless robotic stereotactic biopsies: a consecutive series of 100 cases. J Neurosurg. 2015
Feb;122(2):342-52. doi:10.3171/2014.9. JNS14107. Epub 2014 Nov 7. PMID: 25380111.
[8] Gonenc, B. and Gurocak, H. (2012b). Virtual needle insertion with haptic feedback using a
hybrid actuator with DC servomotor and MR-brake with Hall-effect sensor. Mechatronics,
22(8):1161–1176.
[9] A. Okamura, C. Simone, and M. O’Leary. "Force Modeling for Needle Insertion into Soft Tissue."
IEEE Transactions on Biomedical Engineering, vol. 51, no. 10, pp. 1707–1716, Oct. 2004.
[10] Morel, G. and Szewczyk, J. and Vitrani, M.A. (2012). Comanipulation. Robotique Medicale,
Hermes, publisher. Pages 343-392.
[11] Alex Tsui, Devin Fenton, Phong Vuong, Joel Hass, Patrice Koehl, Nina Amenta, David Coeurjolly,
Charles Decarli & Owen Carmichael (2013). « Globally Optimal Cortical Surface Matching With
Exact Landmark Correspondence ». Information Processing in Medical Imaging, 28 juin 2013,
Asilomar, California (États-Unis), pp. 487-498. HAL : hal-00974838
[12] Thibault Senac, Arnaud Lelevé, Richard Moreau, Laurent Krähenbühl, Florent Sigwalt, et al..
Designing an accurate and customizable epiduralanesthesia haptic simulator. 2019 IEEEInternational Conference on Robotics and Automation (ICRA), IEEE, May 2019, Montreal, Canada. ?
10.1109/ICRA.2019.8794199?. ?hal-02170879?
[13] Ma de los Angeles Alamilla Daniel, Richard Moreau, Redarce Tanneguy. Development of haptic
simulator for practicing the intraarticular needle injection under echography *. EMBC, Jul 2020,
Montreal, Canada. pp.4713-4716, ?10.1109/EMBC44109.2020.9175728?. ?hal-02947141?
[14] Raabe, C., Fichtner, J., Beck, J., Gralla, J., & Raabe, A. (2018). Revisiting the rules for freehand
ventriculostomy: a virtual reality analysis, Journal of Neurosurgery JNS, 128(4), 1250-1257.
Retrieved Dec 9, 2020, from https://thejns.org/view/journals/j-neurosurg/128/4/article-p1250.xml
[15] T. Sénac, A. Lelevé, R. Moreau, L. Krähenbühl, F. Sigwalt and C. Bauer, "Skill assessment of an
epidural anesthesia using the PeriSIM simulator," in IEEE Transactions on Medical Robotics and
Bionics, doi:10.1109/TMRB.2020.3048247.
[16] Jenny Cifuentes-Quintero, Minh Tu Pham, Pierre Boulanger, Richard Moreau, Flavio Prieto.
Towards a classification of surgical skills using affine velocity. IET Science Measurement and
Technology, Institution of Engineering and Technology, 2018, 12 (4), pp.548 - 553. ?10.1049/iet-
smt.2017.0373?.